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Wang, T

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Efficacy and safety of once-weekly semaglutide 24 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 trial

However, research shows that it due to the short half-life of this medication which can be between 2 to 10 minutes (vs 36 hours for hCG), injections a minimum of 6 times daily are needed have a similar clinical effect as two 500iu injections of hCG Once taken, a single dose may be in a patients system and effective from anywhere between 36-72 hours depending on the individual patient, their reaction to the medication and the dose/amount of medication taken