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Description
A previous study identified a set of naturally occurring human regulatory T cell epitopes (Tregitopes), present in the Fc and Fab domains of IgG, that induce tolerance when co-administered with other proteins (119)

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Environmental factors include the place of residence in pre-adult years, smoking, and age of exposure to the Epstein-Barr virus, while genetic factors include 52 identified alleles associated with MS development [3]
