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Description
[0055] Embodiment 48: The antibody of embodiment 11, wherein said antibody contains at least one heavy chain variable region of an M25wtIA antibody

ACHY deficiency is an autosomal recessive disorder associated with hypermethioninemia, failure to thrive, psychomotor impairment, hypotonia, facial dysmorphism, and cardiomyopathy
The role of mitochondrial dysfunction is central to Glial function and even development ( Shifts in mitochondrial metabolism are crucial in the regulation of glial immune cell phenotypes

In particular, LPS, the main component of the outer membrane of Gram-negative bacteria, can cause so-called endotoxemia