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Description
By evading this sequestration, IGF-DES is able to engage the IGF-1 receptor (IGF-1R) more directly, making it a uniquely valuable research tool for studying IGFBP-independent IGF-1 receptor signalling

Have gastrointestinal conditions that impair nutrient absorption (e.g., IBS, celiac disease, or Crohns)

cultivation and use dating back to the Neolithic era

McGuire et al
