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Is Vitamin C necessary with glutathione injections
For the polyglutamylation to be effective and to achieve tissue retention, 5-methyl-THF needs to be first metabolized to THF via the methionine cycle

These include replicative exhaustion due to telomere shortening, DNA damage, oncogene activation, mitochondrial dysfunction, metabolic stress, proteotoxic stress, and exposure to certain inflammatory mediators or mitogens [49]

Berlin, Heidelberg: Springer
