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doi: 10.1146/annurev-immunol-041015-055605, PMID: [DOI] [PubMed] [Google Scholar] Virili C., Fallahi P., Antonelli A., Benvenga S., Centanni M
When amino acids are scarce, mTORC1 senses the fluctuations in amino acid levels and can be suppressed to increase amino acid availability from protein turnover via autophagy for tumor growth
NAD+ precursors change significantly in the body during treatment
According to the Randle hypothesis the fatty acid-induced insulin resistance will result in elevated intracellular levels of both glucose and glucose-6-phosphate (Figure 7)
