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Although a higher lipophilicity should lead to an enhanced cellular uptake, as Pt(IV) complexes (unlike Pt(II) complexes) enter cells solely by passive diffusion, a lack of correlation between log P values and cellular Pt levels is not unprecedented 31,32
[DOI] [PMC free article] [PubMed] 67.Alexander GE
[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Feldman E.L., Callaghan B.C., Pop-Busui R., Zochodne D.W., Wright D.E., Bennett D.L., Bril V., Russell J.W., Viswanathan V
IV therapy delivers glutathione directly into your bloodstream, ensuring that 100% of the antioxidant is absorbed for maximum benefit
