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Clinical trials confirmed no effect on serum IGF-1 levels, no negative effect on carbohydrate metabolism, and no anti-AOD-9604 antibodies detected in any participants

Unlike other anti-CD38 antibodies, TNB-738 does not induce cell death and immunosuppression, leading to a more balanced immune response
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Growth hormone and insulin-like growth factor I treatment increase testicular luteinizing hormone receptors and steroidogenic responsiveness of growth hormone deficient dwarf mice
