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These patients presented with postural instability gait disturbance (PIGD) PD phenotype (Christine et al
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42 Stage 1 symptoms are likely preclinical because the pathology is unlikely to cause long-term clinical manifestations at this point in the disease process
In vitro , CsA downregulates SFRP1 in DP, an inhibitor of the Wnt ligand, which activates the Wnt/-catenin pathway in HF and then induces hair growth 219
