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This relationship is also observed in non-tumor cells, such as chondrocytes, fibroblasts, epithelial cells, osteoblasts, and hepatocytes [71]
78,431 This complexity, which is influenced by clonal evolution, genetic mutations, epigenetic regulation, and interactions with the TME, poses significant challenges in the development of effective CSC-targeted therapies
And it goes back to something I do want to really clarify for listeners
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