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Macrophages consume cystine via a strong membrane transport system, and generate large amounts of cysteine which they release into the extracellular space
It also appears to reduce VEGF (vascular endothelial growth factor) expression (Li 2013), increase expression of the tumor suppressor protein p53, and inhibit COX-2 expression (Lu 2012)
First, we generated L MW SS by incubating GSH with DTNB to generate GS-TNB, which was then converted into GSS by addition of Na 2 S, as indicated by TNB release at both steps (Fig
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