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The frequency of the vitamin B12 injections depends solely on the individuals health needs, such as age, underlying cause of malabsorption, dietary habits, medication and most importantly, response to the injection

In these circumstances a series of routine injections followed by a maintenance period to evaluate and monitor the effects is recommended

DNA testing required for formal diagnosis (not a first-line investigation, exclude other causes first) Pre-pregnancy carrier testing of partner is important Rare causes of microcytic anaemia Chronic inflammation Lead poisoning (high blood lead level) Sideroblastic anaemia Normocytic normochromic anaemia Haemolytic anaemia Acute haemolysis in childhood can be a life-threatening illness and all cases should be discussed with a haematologist Admit children with haemolytic anaemia for observation

Niacinamide is sometimes included in GLP-1 formulations to support energy pathways and improve overall metabolic function