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(14) While some studies suggest B12 could be beneficial in treating insomnia and sleep disorders, other studies remain largely inconclusive or link high-dose B12 to sleep impairment and short sleep duration - the opposite of what we want

Do You Need a Prescription for B12 Shots

The skillful support of Jana Golombek and Lena Klusik in the organization and technical conduct of the surveys is gratefully acknowledged

According to the NIH Office of Dietary Supplements, functional B12 deficiency is most commonly seen in patients with one or more of the following: Age over 50 stomach acid production declines with age, and stomach acid is required to free B12 from food PPI or H2 blocker use reflux medications suppress the acid needed for B12 absorption Metformin use, which interferes with B12 absorption directly Vegan or vegetarian diets B12 is found almost exclusively in animal products Gut conditions including celiac, IBS, SIBO, and Crohns MTHFR mutations that affect how B12 is metabolized once absorbed Heavy alcohol use The symptoms of low B12 are easy to dismiss: fatigue, brain fog, low mood, tingling in the hands or feet, weakness, and shortness of breath on mild exertion