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Hu X-T, Dong Y, Zhang X-F, White FJ (2005) Dopamine D2 receptor-activated Ca2 + signaling modulates voltage-sensitive sodium currents in rat nucleus accumbens neurons

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There have been several documented cases of patients with Parkinson's disease in the absence of Lewy pathology, who have parkin-related disease and in some cases a mutation in the LRRK2 gene

It is an intracellular metabolic-enzyme modulator, which is why its research read-outs are things like NAD+ levels and adipocyte gene expression, not how full you feel. That mechanistic distinction is the single most important thing to understand before looking at any dose number