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Shu L., Yang M., Liu N., et al., Short Hexapeptide Optimized From RiceDerived Peptide 1 Shows Promising AntiHyperuricemia Activities, Journal of Agricultural and Food Chemistry 70 (2022): 66796687, 10.1021/acs.jafc.2c00354

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Over the past couple of years, several reviews have been published in academic journals by researchers at major universities in the U.S., Britain, and Poland

However, in glutathione synthetase deficiency, because the activity of gamma-glutamyl-cysteine synthetase is regulated via feedback inhibition by glutathione, gamma-glutamyl-cysteine and then L-5-oxoproline are overproduced, resulting in the metabolic acidosis and urinary excretion of this compound at levels several hundred-fold above normal (71