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How This Works Semaglutide is a GLP-1 receptor agonist : it mimics the incretin hormone GLP-1 to enhance glucose-dependent insulin secretion, slow gastric emptying and reduce appetite [1] [2]

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Dimitris Papamargaritis, an associate professor in diabetes and endocrinology at the University of Leicester, says animal studies suggest that amylin analogs can spare muscle, which is why several companies have decided to look at amylin with a fresh set of eyes

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