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The introduction of the NO-synthase inhibitor L-NAME (1 mol/L) into the perfusing solution 20 min before the acetylcholine reduced the vasodilator responses of aortic rings to acetylcholine in 9.41 times ( p = 0.003) (Figure 5C)
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doi:10.1016/j.biochi.2020.04.004 Araki R, Maruyama C, Igarashi S, et al

Tumor associated macrophages, as the dominant immune cells, are an indispensable target for immunologically cold tumor-glioma therapy
