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Description
Written informed consent for participation was not required from the participants or the participants legal guardians/next of kin because data were obtained from administrative datasets encompassing primary, secondary, and tertiary care for Brazilian patients across all five geographic regions (North, Northeast, Central-West, South, and Southeast)
The presence of a tingling sensation or numbness are one of the first signs of vitamin B12 overdose
So the signals cannot pass from the nerve to the muscle any more
For higher doses or when absorption is poor, they can be given through a vein
