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Related disorders such as allergies, mast cell disorders, and gastrointestinal conditions are also looked at while trying to diagnose this condition

[69] studied the function of rice OsAPX2 gene using a T-DNA knockout mutant under the treatment of drought stress, founding that loss of function in OsAPX2 affected the growth and development of rice seedlings, resulting in semi-dwarf seedlings, yellow-green leaves, leaf lesion mimic and seed sterility

Table 3: Dose Reduction for Pemetrexed (single-agent or in combination) and Cisplatin Neurotoxicity Discontinuation Recommendation: Pemetrexed therapy should be discontinued if a patient experiences any hematologic or nonhematologic Grade 3 or 4 toxicity after 2 dose reductions or immediately if grade 3 or 4 neurotoxicity is observed

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