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Coronary microvascular dysfunction may be related to IGF-1 in acromegalic patients and can be restored by therapy

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Am J Kidney Dis 46: e4e10, 2005 [DOI] [PubMed] [Google Scholar] 14.Humphreys BD, Forman JP, Zandi-Nejad K, Bazari H, Seifter J, Magee CC: Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglutamic aciduria) acquired in hospital

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In fact, over 14,000 new cases of anemia are reported annually in the elderly, underscoring the prevalence of this condition in this demographic

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Together, our observations that a small molecule NNMT inhibitor can increase NAD + and SAM concentrations in differentiated adipocytes and reduce adiposity in DIO mice, suggest that treatment with an NNMT inhibitor effectively reverses obesity via modulation of the NAD + salvage and SAM-mediated (e.g., polyamine flux) pathways to regulate energy expenditure in the adipose tissue

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