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TB-500 thus exhibits similar behavior and outcomes to TB4 in clinical studies
Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice

Safety, tolerability, and exploratory indicators of mitochondrial functioning were included among the secondary objectives ( Another 2021 open-label, single-center Phase I trial NCT04976127 looked at the safety, tolerability, and pharmacokinetics of intravenous TalineurenTM (TLN), a liposomal GM1 ganglioside for PD
