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[6] Release of GST-A1 as an indication of cellular necrosis [edit] Increases in serum and urinary GST-A1 have been found in association with hepatocyte and renal proximal tubular necrosis respectively, and have potential for monitoring injury to these tissues

The correlation was enhanced with the presence of the APOE 4 allele

doi: 10.1007/s12035-016-0170-2 134 TateWWalkerMSweetmanEHelliwellAPeppercornKEdgarCet al

Up-regulation of gasdermin C in mouse small intestine is associated with lytic cell death in enterocytes in worm-induced type 2 immunity