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Description
In some cases, the case can never be reopened
Mechanisms are multi-pathway: Neurotrophin effects (BDNF), immune gene expression shifts, and receptor-level melanocortin activity have all been described
Future studies integrating longitudinal clinical data and mechanistic interventional approaches will be essential to clarify these relationships and their therapeutic relevance
Yang L., Gilbertsen A., Smith K., Xia H., Higgins L., Guerrero C., Henke C
