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NAD+-dependent sirtuin activation in endothelial cells promotes antioxidant enzyme expression, reduces inflammatory responses, and enhances nitric oxide synthase activity, leading to improved endothelial function and vascular health

Rather than asking what is the dose, which presumes the compound is already the answer, the stronger questions open up the actual decision

[PubMed] [Google Scholar] Sikiric P, Separovic J, Anic T, et al
Refrigeration is key when it comes to storing this water
