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If ECG changes are persistent or worse, this increases the likelihood of plaque rupture
As the field develops, direct measurement of circulating MOTS-c may become a useful biomarker for guiding dose adjustments, similar to how IGF-1 is used to monitor growth hormone or testosterone levels guide TRT dosing

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Connective tissue remodeling Remodeling allows newly formed collagen fibers to organize in a way that supports tendon strength and flexibility
