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WT mice was calculated for individual replicates, averaged, and converted to a log2 scale

It lowers the glass transition temperature of the dried cake, essentially allowing molecular movement to resume at storage temperatures that would otherwise be safe

Glossary FDA Federal Drug Administration ITT intent-to treat PP per protocol MWW MannWhitneyWilcoxin C TTmean mean total testosterone concentration C TTmax maximum total testosterone concentration C TTmax minimum total testosterone concentration C TT0h testosterone concentration at time 0 of each 24-h sampling period C TTrange range of total testosterone concentration AUC area under the curve BMI body mass index TSH thyroid-stimulating hormone ACTH adenocorticotropic hormone hGH human growth hormone C LHmean mean concentration of LH Conflict of Interest None declared

Dogs: 1 - 2mL i.m