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[DOI] [PubMed] [Google Scholar] 116.Xu Q, Fu Q, Li Z, et al

It is formed by two sulfur atoms linked through a disulfide bond, which remains stable under physiological conditions but enables precise drug release via disulfide linker cleavage in highly reductive environments such as tumor cells

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For example, EPI may enter autoxidation due to ROS generation ( 3 Role of mitochondria in preventing/treatment of oxidative stress in PTSD Available data indicate that mitochondrial dysfunction, or suboptimal functioning, inherited or acquired, contribute to the manifestation of PTSD symptoms and can increase susceptibility to PTSD (for review, see, e.g., 3.1 Mitochondria-derived peptides Mitochondria-derived peptides (MDPs), also known as mitochondrial microproteins, are encoded by short open reading frames (ORFs) located in mitochondrial DNA (mtDNA) (e.g., According to PubMed, the most well-studied of these MDPs is humanin