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Subsequently, the pRB-E2F-TAg complex associates with Hsc70 in the presence of ATP as Hsc70 ATP-bound form presents high substrate association rate to facilitate TAg-Hsc70 complex formation
Furthermore, IL-6 inhibits PPAR expression in human hepatocytes [61]
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Receptor uncoupling [edit] Receptor uncoupling/phosphorylation is the most rapid form of desensitization that happens within a cell, as its effects are seen within seconds to minutes of agonist application
