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Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice
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Acetyl-CoA carboxylase 1 (ACC1), the rate-limiting enzyme in FA biosynthesis, which is negatively regulated by TRIB3 46 , was markedly reduced in Cse / mice compared with in Cse +/ mice on the no-Cys diet (Figs

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