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Bone defect models are commonly used in such studies

Furthermore, primary myoblasts isolated from both Mstn -null mouse embryos and adult mice were shown to exhibit a significantly increased proliferation rate 64 , and skeletal muscle regeneration after toxin-induced injury was significantly enhanced in Mstn -null mice 65,66 , indicating that endogenous MSTN suppresses satellite cell proliferation, differentiation, and muscle regeneration

These results may be explained by the different factors that influence zinc homeostasis by modulating intestinal absorption and urine excretion, leading to different serum zinc levels

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