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The increased production of TMAO has been linked to various health conditions, like cardiovascular diseases, atherosclerosis and stroke as mentioned above [24]

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When the analysis was limited to individuals diagnosed with psychiatric disorders, the results indicated that the combinations of OLZ+VPA and QUE+VPA elevated the risk of HE by 1.65 times (OR = 1.65, 95% CI [1.18, 2.30]) and 1.95 times (OR = 1.95, 95% CI [1.39, 2.75]), respectively
