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the adverse reaction must be unexpected, that is to say, the nature and severity of the adverse reaction are not in agreement with the product information as recorded in: a) summary of Product Characteristics (SPC) for an authorized medicinal product

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This fiber restriction significantly affects the composition and diversity of the gut microbiota, particularly by depleting beneficial butyrate-producing bacteria in the Firmicutes phylum (e.g., Faecalibacterium prausnitzii , Roseburia spp.) [92,93]

See how you go, leaving the patient stunned