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XO4 + microglia exhibited dysregulated expression of AD-associated genes, while XO4 microglia showed transcriptional signatures resembling accelerated aging and reduced phagocytic capacity
It has been effective in lowering MMP-9 levels, which are a marker of inflammation

An example of this is the Tdap (Tetanus, diphtheria, and acellular pertussis) vaccine

10.1016/j.bbamcr.2020.118707 4 ArmahC
