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MTHFR Gene Polymorphisms in Diabetes Mellitus
Some people also take it for treating aging, liver and heart diseases, alcohol use disorder and many more such conditions

The active metabolite of folate, 5-methyltetrahydrofolate (5-MTHF, L-methylfolate), participates in re-methylation of the amino acid metabolite homocysteine, creating methionineThere are few intervention studies of folic acid or 5-MTHF as a stand-alone treatment for depression related to folate deficiency

and these tend to resolve quickly
