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Researchers planning new work should review the most current literature before designing protocols, with attention to the gap between preclinical breadth and clinical-trial depth

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doi: 10.1016/ j.celrep.2022.111214 183

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Bcl-2 is posited as an anti-apoptotic protein that apparently inhibits cell death, while Bax is suggested to be a pro-apoptotic protein that promotes cell death

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