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Oxidative stress and aging: Synergies for age related diseases

The exact reason for the age-related decline in plasma GHK-Cu levels is not fully understood

These drugs reduce ROS generation through multiple mechanisms: by enhancing mitochondrial biogenesis and fusion (via PGC-1), activating cAMP/PKA and PI3K/Akt pathways, increasing expression of antioxidant enzymes such as SOD2 and catalase, and restoring endothelial NO bioavailability [449,450]

Peptides represent a fascinating frontier in medicine, but they must be approached with caution and a clear understanding of their current regulatory and scientific status