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This study has some limitations, such as the fact that the search was limited to PubMed and to the last 20 years
While these substances offer potential benefits, their safety and efficacy are still subjects of ongoing research, and their use should be approached with caution
Skin adverse reactions were also reported, such as injection site pain, pruritus, rash, and urticaria, but only a few cases of acneiform eruptions [5]
