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Moreover, since the infections with parasites occurred after onset of MS, these studies show that parasitic infections may also be of therapeutic use in patients with ongoing disease, in addition to a prophylactic potential

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The dysregulation of TfR1, DMT1, and other iron transporters, in conjunction with BBB compromise and neuroinflammatory signals, may potentiate oxidative stress and thereby render neurons particularly susceptible to ferroptotic cell death

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