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It was noted that protection mediated by passive transfer of immune sera was lost in mice lacking expression of activating FcRs, in particular FcRIII, or depleted of alveolar macrophages

Its primary function is in tissue repair: it promotes actin polymerization (required for cell movement), upregulates anti-inflammatory proteins, and stimulates the migration of keratinocytes and endothelial cells that are needed to close and repair damaged tissue
For shoulder tendons that need robust, properly organized collagen to regain strength, this is significant

Inflammopharmacology 14(56):214221 Sikiric P, Seiwerth S, Brcic L, Sever M, Klicek R, Radic B, et al (2010) Revised Robert's cytoprotection and adaptive cytoprotection and stable gastric pentadecapeptide BPC 157
