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Similarly, studies in thyroid cancer have shown that downregulating MTH1 expression, particularly when combined with drugs regulating the glutathione pool, increases ROS levels in cancer cells

doi: 10.1056/NEJMoa1912196 95 van VollenhovenRAskanaseADBombackASBruceINCarrollADallEraMet al

The answer at Perfect B is not to dismiss the concern or ignore the evidence
