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Mechanistically, -sitosterol can induce cancer cell apoptosis by modulating key regulators: it elevates the Bax/Bcl-2 ratio and activates caspases via the intrinsic mitochondrial pathway

Gmez V, Eykyn TR, Mustapha R, Flores-Borja F, Male V, Barber PR, Patsialou A, Green R, Panagaki F, Li CW, et al

Mitochondria not only provide muscle with the necessary fuel, but also release and integrate exercise-induced signaling

Short-chain fatty acid metabolism and multiple effects on cardiovascular diseases