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Persons afflicted with an inherited form of Wernicke-Korsakoff syndrome appear to have an inborn error of metabolism that is clinically important only when the diet is inadequate in thiamine

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Despite often being grouped with peptides in longevity content, 5-amino-1MQ is a small synthetic molecule that works by blocking an enzyme that breaks down a building block of NAD+

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In contrast to the higher mVCN detected in the patients who achieved transfusion independence, these two patients had mVCN of 0.139 and 0.328, with no or 2.52 g/dL total unsupported hemoglobin, respectively

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doi: 10.1348/1359107041557048

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