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[DOI] [PubMed] [Google Scholar] 96.Baran W., Batycka-Baran A., Zychowska M., Bieniek A., Szepietowski J

These studies aim to understand how tesofensine measures up against existing treatment options, providing valuable data for healthcare providers and patients alike

For instance, hypoxia induces extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation to activate HIF-1, which directly binds to the promoter of ABCG2 gene and subsequently enhances ABCG2 transcription, leading to gemcitabine chemoresistance in pancreatic cancer cells (He et al., 2016)

This review underscores the need for continued exploration and optimization of CAR-T strategies to address the unmet needs of SLE patients