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This is intriguing, as A also undergoes a similar oligmerization process forming a hexameric barrel which also resembles a channel shape in its protofibrilar state, and which has neurotoxic properties, as demonstrated by A 142 (Lendel et al., 2014
They're placed at the ends to ensure no vital data gets left behind
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MedComm (2020) 6(7):e70268
