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This proposed sequential mechanism for dysbiosis-related IBD indicates that dysbiosis regarded by a reduction in butyrate-producing bacteria and a raise in SRBs results in a lower level of butyrate, which leads to a decrease in epithelial tight junction protein expression and thus continued to increase colonic epithelial permeability, which leads to increased bacterial translocation through the intestinal epithelial cells and lamina propria (Rigottier-Gois, 2013)

doi: 10.1016/j.nut.2018.11.015 178 WeberATShahNDSaukJLimketkaiBN

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