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Underlying Causes: The specific pathogenesis can vary based on the underlying cause of B12 deficiency: Dietary deficiency: Inadequate intake of B12, common in vegans and vegetarians
This allows for higher bioavailability and more efficient correction of deficiencies compared to oral supplements, particularly for individuals with absorption issues or significant deficiencies

Protective packaging: Peptides are light- and temperature-sensitive

Certain eye drops, especially the ones used to treat glaucoma, are known to cause dermatitis that, in turn, causes dark circles in the under-eye area
