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Research Highlights Metabolic Regulation and Anti-Obesity Effects: Potent inhibition of nicotinamide N-methyltransferase (NNMT) increases cellular NAD and S-adenosylmethionine (SAM) levels, enhances polyamine flux, boosts energy expenditure, and suppresses lipogenesis
Zhao Y, Fu L, Li R, Wang L-N, Yang Y, Liu N-N, Zhang C-M, Wang Y, Liu P, Tu B-B
Persistent or significant joint pain may indicate that the dose is too high
