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Description
1 3 L-Carnitine 3 6 ( )
The mouse model for OTC deficiency has decreased mitochondrial complex IV activity, decreased mitochondrial detoxification capacity, and reduced ATP levels in brain (54)
The resin itself (cholestryamine) is not absorbed from the GI tract
3.3 Reduced BDNF expression Brain-derived neurotrophic factor (BDNF) is an important neurotrophic substance in the central nervous system, which binds to Tropomyosin receptor kinase B (TrkB) receptors on postsynaptic neurons to promote synaptic strengthening and the formation of new synapses (56), consequently ensuring neuronal survival (57)
