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[PUBMED Abstract] Abdel-Rahman MH, Pilarski R, Cebulla CM, et al.: Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers
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Importantly, such domains can serve as selective barriers to membrane inheritance: the long chains of sphingolipids, especially in an ordered state, present a relatively thick lipid bilayer, which tends to exclude membrane proteins with short transmembrane domains (TMDs) due to hydrophobic mismatch (Singh et al., 2017) and resulting reduction in culture lifetimes
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