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Description
Whereas low ROS levels lead to SENP3 accumulation and therefore enhanced HIF1 transcriptional activity, high concentrations of ROS inactivated SENP3 resulting in the suppression of HIF1 transcriptional activity

The modelling of Metro into the HpTpx- Metro-P3 * co-structure demonstrated a precise fit within the substrate binding pocket (Supplementary Fig
The expression plasmid for the above E3 ubiquitin ligase was transfected into CC cells, and RT-qPCR corroborated the validity of overexpression (Fig

Potential biomarkers of mitochondrial dysfunction associated with COVID-19 infection
